Nutraceuticals in dyslipidemia management
Sunil K Kota1, Sruti Jammula2, Siva K Kota3, Surabhi Venkata Satya Krishna1, Lalit K Meher4, Epari Sanjeeva Rao5, Kirtikumar D Modi1
1 Department of Endocrinology, Medwin hospital, Hyderabad, Andhra Pradesh, India
2 Department of Pharmaceutics, Roland Institute of Pharmaceutical Sciences, Berhampur, Orissa, India
3 Department of Anesthesia, Central Security hospital, Riyadh, Saudi Arabia
4 Department of Medicine, MKCG Medical College, Berhampur, Orissa, India
5 Department of Pathology, KIMS Research & Foundation, Amalapuram, Andhra Pradesh, India
Sunil K Kota
Department of Endocrinology, Medwin Hospitals, Chiragh Ali Lane, Nampally, Hyderabad-500001, Andhra Pradesh
Source of Support: None, Conflict of Interest: It is submitted with the full knowledge and approval of our institute and there is no conflict of interest to disclose from any of the authors with regards to publication of the manuscript or an institution or product that is mentioned in the manuscript. There are no competing interests to disclose, due to any reasons, with whom so ever concerned.
With the ever increasing epidemic of obesity, diabetes and hypertension among young adults, the risk of mortality and morbidity due to atherosclerotic heart disease is gradually increasing. Dyslipidemia is an additional risk factor for cardiovascular disease. Nutraceutical supplements can provide valid alternate to patients who are intolerant to statins or patients preferring alternative treatments. The combination of a lipid lowering diet and scientifically proven nutraceutical supplements can significantly reduce low density lipoprotein (LDL) cholesterol, increase LDL particle size, decreased LDL particle number decreased triglycerides and increased high density lipoprotein (HDL) particles. In addition, they address lipid induced vascular damage by suppressing inflammation, oxidative stress and immune response leading to additional antihypertension, antidiabetic properties. The current article reviews the evidence in support of different dietary supplements and their lipid lowering beneficial effects.