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REVIEW ARTICLE
Year : 2012  |  Volume : 1  |  Issue : 2  |  Page : 83-86

Role of anti-oxidants in prevention of age-related macular degeneration


Department of Ophthalmology, MGM Medical College, Navi Mumbai, Maharashtra, India

Correspondence Address:
Shrikant Deshpande
Flat No 303, Shri sai sagar CHS, Plot No 80/81, Sector-19, Kharghar, Navi Mumbai-410210
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2278-019X.101292

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Age-related macular degeneration (ARMD) is the most common cause of severe, irreversible, vision loss in elderly people. It is estimated that 20 to 25 million people suffer from ARMD worldwide, of which 8 million people experience blindness. The treatment options are few and usually not successful in restoring the vision back. The anti-oxidants prevent the damage to the macula by free radicals and are beneficial in retarding the progress of ARMD. They also prevent the onset of ARMD. Anti-oxidant supplements are indicated to prevent the onset and retard the progression of ARMD. The Age-Related Eye Disease Study found that the daily supplementation of vitamin C 500 mg, vitamin E 400 IU and beta carotene 15 mg, zinc 80 mg and copper 2 mg for five years significantly retarded the progression of ARMD. Based on the results of this high quality, double blinded study, the American Academy of Ophthalmology recommends that patients with intermediate and severe ARMD consider taking antioxidants plus zinc on a daily basis.


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