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REVIEW ARTICLE
Year : 2012  |  Volume : 1  |  Issue : 2  |  Page : 63-76

Nutraceuticals in pathogenic obesity; striking the right balance between energy imbalance and inflammation


1 Department of Endocrinology, Medwin Hospital, Hyderabad, Andhra Pradesh, India
2 Department of Pharmaceutics, Roland Institute of Pharmaceutical Sciences, Berhampur, Orissa, India
3 Department of Anesthesia, Central Security Hospital, Riyadh, Saudi Arabia
4 Department of Medicine, MKCG Medical College, Berhampur, Orissa, India
5 Department of Pathology, KIMS Research & Foundation, Amalapuram, Andhra Pradesh, India

Correspondence Address:
Sunil K Kota
Resident in Endocrinology, Department of Endocrinology, Medwin Hospitals, Chiragh Ali Lane, Nampally, Hyderabad - 500001, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2278-019X.101288

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Obesity leads to chronic, excessive adipose tissue expansion resulting in an increase in the risk for cardiovascular disease, type 2 diabetes mellitus, and other metabolic abnormalities. This is primarily thought to stem from the low-grade, systemic inflammatory response syndrome that characterizes adipose tissue in obesity. With a global increase in the prevalence of obesity, nutrition and exercise play a key role in its prevention and treatment. Natural product (nutraceutical) interventions are currently being investigated on a large-scale basis as potential treatments for obesity and weight management. Apart from taking care of the imbalance between energy intake and energy output, nutraceuticals should have the potential to ameliorate the development of oxidative stress and inflammation in obesity, thereby limiting the onset of obesity complications. The current article aims to examine current research on nutraceuticals and their role in the management of obesity and body composition.


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